Here are some ways that can try to minimize the virus enter into Hardisk.
The first way –> Disable Autorun and Autoplay through Group Policy [GPEDIT.MCS]
1. Click Start Menu
2. Click Run
3. Type gpedit.msc, and OK / press Enter
4. In the User Configuration click 2x (left pane)
5. Double click on Administrative Templates (right window)
6. Then double-click System
7. Double click on Turn Off Autoplay
8. In the Settings section select Enable, then on Turn Off Autoplay on select All Drives
9. Click Apply, then OK,
10. Then Restart Computer.

The second way –> Disable Autorun / Autoplay through registry
1) Open the Registry Editor
2) Click [Start Run dialog box on RUN type regedit]
3) Browse to the following registry address: HKEY_CURRENT_USER – Software – Microsoft – WindowsCurrentVersion – Policies – Explorer – HKEY_USERS.DEFAULT – Software – MicrosoftWindows – CurrentVersion – PoliciesExplorer
4) Then right click on the string NoDriveTypeAutoRun
5) Address registry that must be modified so as not autorun active
6) Fill out the data value with the mean function “ff” Autorun / Autoply will turn off at 255 drive
7) Change the value NoDriveTypeAutorun
8 ) Click the [OK]
9) Quit “Registry Editor”
10) Restart the computer

The third way –> Disable extension.exe
1. Select Start>> Control Panel
2. Select Administrative Tools> Local Security Policy
3. Select Software Restriction Policies>> Additional Rules
4. Right-click on Additional Rules>> select New Path Rule …
5. In the Path column, select flshdisk Browes select which drives are, for example in I: \
6. In the Security Level field, select Disallowed
7. Select OK and Restart your computer

Hope this tips can be make your computer better.